Prediabetes
Conditions
Interventions
Intervention group:Take 10g of DEXtrin every day before lunch
Control group:Placebo maltodextrin 4.7g/d before lunch every day
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. People aged 35-75, regardless of gender; 2. BMI between 18 and 32kg/ m2, stable body weight (+/-4 kg) in the past 2 months; 3. Diagnosis of prediabetes-impaired fasting glucose: fasting glucose between 6.1 and 7.0mmol/ L and blood glucose < 7.8mmol/ L 2 hours after glucose load or diagnosis of prediabetes -- impaired glucose tolerance: fasting glucose < 7.0mmol/ L and blood glucose between 7.8 and 11.1mmol/ L 2 hours after glucose load; 4. Understands and agrees to participate in a study.
Exclusion criteria
Exclusion criteria: 1. HbA1c concentration >7% was excluded. 2. Pregnancy and lactation were excluded; Patients suffering from serious acute or chronic diseases, such as malignant tumors; 3. Exclude people who have diseases that raise blood sugar or take drugs that affect blood sugar; 4. People taking diabetes medications were excluded; 5. Exclude any other diseases or conditions that may limit study adherence; 6. People with daily dietary fiber intake of more than 30g were excluded; 7. Exclude glucocorticoids, antibiotics, prebiotics, probiotics, vitamin supplements, and any other drugs that might interfere with microbiome analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FBG(fasting blood-glucose);2h postprandial blood glucose;Glycosylated hemoglobin;Insulin resistance index;C-reactive protein;Triglyceride;High density lipoprotein (HDL);Low density lipoprotein (LDL);Cholesterol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;Weight;Waistline;Hipline;Blood pressure; | — |
Countries
China
Contacts
Public ContactLiyong Chen
Qilu Hospital of Shandong University
Outcome results
None listed