Hypertension
Conditions
Interventions
control group :Use a therapeutic device that is identical in appearance and usage to the treatment group, for a total of 14 days.
treatment group:Use a therapeutic device that can emit low-intensity pulsed ultrasound for ultrasound intervention at the marked location on the body surface of the renal hilum, for a total of 14 days
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 18-65, newly diagnosed by a cardiologist with mild primary systolic-diastolic hypertension (i.e., not currently using antihypertensive drugs), defined as one of the following situations:? Clinic blood pressure measurement results show systolic blood pressure =140mmHg and diastolic blood pressure =90mmHg, and systolic blood pressure <160mmHg and diastolic pressure <100mmHg, with all three measurements on different days reaching the above thresholds;? Dynamic blood pressure monitoring results show 24-hour average systolic/diastolic pressure =130/80mmHg, daytime =135/85mmHg or night-time =120/70mmHg.(2) Body Mass Index (BMI) is between 18.5-23.9;(3) The patient agrees and signs an informed consent form, and can complete follow-ups and examinations during the entire clinical research period.
Exclusion criteria
Exclusion criteria: (1) Secondary hypertension;(2) Existence of uncontrolled comorbidities (comorbidities refer to accompanying uncontrolled active coronary heart disease, heart failure, stroke, peripheral arterial atherosclerosis, kidney disease, diabetes) or other active systemic diseases (including liver, kidney failure disease; malignant tumor; moderate or above anemia; Parkinson's syndrome etc.);(3) Pregnant and lactating women;(4) History of cardio/cerebral pacemaker implantation;(5) Those who need to take anticoagulants long-term for various reasons (including warfarin or new oral anticoagulants such as rivaroxaban, apixaban, edoxaban, dabigatran, etc.);(6) Patients who have undergone renal artery RF ablation for hypertension;(7) Having active poorly controlled mental illness, including delusions, hallucinations or suicidal intentions, etc.;(8) History of alcohol or drug addiction;(9) Those who are simultaneously participating in other clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour ambulatory systolic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Routine blood test;routine urine test; | — |
Countries
China
Contacts
Public ContactDong Huang
The Sixth People's Hospital Affiliated to Shanghai Jiaotong University,School of Medicine
Outcome results
None listed