In vivo study of SSP/SWEEPS-ER: YAG laser-activated irrigation for root canal therapy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062410

Enrollment

Unknown

Registered

2022-08-05

Start date

2022-08-06

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulp and periapical disease

Interventions

Experimental group 1:PIPS+3%NaOCl+17%EDTA

Experimental group 2:SWEEPS+3%NaOCl+17%EDTA

Experimental group 3:PUI+3%NaOCl+17%EDTA

Experimental group 4:EDDY+3%NaOCl+17%EDTA

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. Patients with pulp and periapical disease with closed apical foramen; 3. Gender is not limited.

Exclusion criteria

Exclusion criteria: 1. Pulp chamber opening, pulptomy or root canal therapy; 2. Immune promise(i.e. using corticosteroids); 3. Infectious disease (such as HIV, hepatitis B, hepatitis C, tuberculosis, BCE or prion); 4. Oral and maxillofacial tumor history; 5. Cancer history in the past two years; 6. History of radiotherapy for head and neck; 7. Tooth mobility >=2; 8. Periodontal pocket depth >=6mm; 9. Opening apical foramen or incomplete apical development; 10. Affected teeth that need piling a post; 11. Vertical or horizontal root fractures below the cemento-enamal junction (CEJ); 12. Adjacent teeth requiring root canal treatment;13.Non-odontogenic facial pain.

Design outcomes

Primary

Measure	Time frame
Bacterial quantity;PAI (Periapical index) scores;Pain degree;	—

Countries

China

Contacts

Public ContactYing Li

Tianjin Stomatological Hospital

liying9211@126.com+86 13752332034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026