depression
Conditions
Sponsors
The Affiliated Brain Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-85 years old, gender is not limited; 2. Meet the diagnostic criteria for Major Depressive Disorder in the American Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-IV); 3. HAMD-17 items >= 17 points; 4. The past 4 weekly medication regimen was stable; 5. Did not receive transcranial magnetic stimulation, transcranial electrical stimulation and electroconvulsive therapy within the past 6 months; 6. The audiovisual level was sufficient to complete the examinations required for the study; 7. Agree to participate in this study and sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Meet any other diagnostic criteria of DSM-IV axis I; 2. High suicide risk: those who currently have suicidal thoughts or suicide plans, or those who score 3 or 4 points for suicide on the HRSD-17 scale, or those who have a high risk of suicide in the judgment of the investigator Suicide risk; 3. Hypothyroidism, major physical diseases such as heart,liver,and kidney cannot tolerate this study; 4. Central nervous system infection, stroke, hydrocephalus, brain tumor, epilepsy and other neurological diseases; 5. Figure confirms epileptiform discharge; 6. Taking anticonvulsant drugs; 7. Currently taking psychological treatment; 8. Contraindications to MRI examination: installation of cardiac pacemaker, arterial clips after craniocerebral surgery; 9. There are ferromagnetic substances in the body, such as Metal foreign body retention, etc.; artificial metal valve after heart surgery; 10. Metal prosthesis, metal joint replacement; insulin pump, nerve stimulator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 17-HAMD; | — |
Countries
China
Contacts
Public ContactXiaomei Zhong
Outcome results
None listed