Chronic Obstructive Pulmonary Disease
Conditions
Interventions
helmet CPAP:helmet CPAP
noninvasive nasal mask:noninvasive nasal mask
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1)Adults >= 18 years old; 2)Diagnosed with COPD; 3)patients with an indication for partial-assisted ventilaton; 4)Intact airway system; 5)Subjects were conscious with spontaneous breathing; 6)Subjects voluntarily participated in this trial, signed the informed consent, and complied with the follow-up process.
Exclusion criteria
Exclusion criteria: 1)Preexisting Cardiac arrest/cardiopulmonary resuscitation history/Severe cardiac dysfunction (Ejection fraction <25%)/pericardial tamponade; 2)GCS score <12; 3)septic shock who did not respond to fluid resuscitation or vasopressor infusion(SBP <90 mmHg); 4)Decompensated respiratory acidosis(PH<7.30; 5)Subjects with airway obstruction/dysphagia or swallowing disorders/high risk of aspiration; 6)Subjects with pneumothorax /barotrauma/upper abdominal or thoracic surgery within 1 month; 7)Planned intubation and mechanical ventilation imminent; 9)Subjects with cervical spine injury/impaired hearing or vision/history of claustrophobia; 10)Identifiable nasal or facial deformities; 11)Endotracheal intubation/ mechanical ventilation within 7 days; 12)Subjects with advanced tumour/multiple organ failure; Pregnant or lactating females; 13)Participation in another clinical trial; 14)Any absolute contraindication to helmet CPAP or noninvasive nasal mask.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SpO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Blood Pressure;Respiratory rate;Comfort level evaluation(VAS); | — |
Countries
China
Contacts
Public ContactYuanda Xu
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed