Anesthetic effect during painless bronchoscopy
Conditions
Interventions
Sponsors
Mindong Hospital Affiliated to Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Plan to undergo elective electronic fiber bronchoscopy under general anesthesia; 2. 18<=age<=65, ASA?-?, 18<=BMI<=30 kg/m2; 3. No hearing, visual or intellectual impairment, and no other conditions that make it difficult to assess the degree of postoperative recovery.understand the basic principles of the experiment and signe an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from mental and neurological diseases (schizophrenia, Alzheimer's disease, epilepsia,etc.); 2. Electrolyte metabolism disorder before surgery, such as K+ = 5.5mmol/L; 3. Severe liver dysfunction, defined as ALT, AST, GGT and other related indicators >= 1.5 times normal value; 4. Severe renal inadequacy; 5. Serious cardiovascular and cerebrovascular diseases, such as unstable angina pectoris or myocardial infarction in the past six months, past severe angina pectoris, congestive heart failure, high-risk coronary artery disease, etc 6. Cannot breathe through the nose for various reasons; 7. Mallampati grade >=3 or combined with OSAHS; 8. Nasopharyngeal airway is contraindicated; 9. Patients with anticipated difficult airway, severe respiratory disease, acute respiratory tract infection, uncontrolled asthma and unexplained dyspnea; 10.Non-invasive arterial blood pressure monitoring is contraindicated; 11.Long term of alcoholism ,drug taking or drug abuse; 12.Allergic to active ingredients or related excipients of drugs used in the study; 13.Participated in other clinical trials within the last 3 months; 14.Other conditions that are not suitable for this clinical trial as judged by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| MOAA/S score;blood pressure;heart rate;incidence of hypoventilation;cough score;intraoperative drug consumption;ncidence of adverse events;satisfaction;induction time;pain injection; | — |
Countries
China
Contacts
Public ContactHuang Qingqing
Outcome results
None listed