flow velocity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.singleton pregnancy at gestational age >= 37 weeks; 2. Age >= 18 years; 3. Active delivery (cervical dilation > 3 cm and uterine contractions at least every 5 min); 4. Gestational hypertension or preeclampsia; 5. ASA physical status I - II; 7. Obstetricians evaluate possible vaginal delivery.
Exclusion criteria
Exclusion criteria: 1. Contraindications to epidural anesthesia; 2. Diabetes mellitus, cardiovascular, respiratory or liver and kidney diseases, history of taking sedative or hypnotic drugs, history of neuropsychiatric diseases; 3. Participating in other clinical intervention trials; 4. Refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulsatile index of uterine artery in placental side of parturient women 30 min after programmed intermittent epidural anesthetic bolus for Labor Analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulsatile index, Resistance index (RI) and systolic-diastolic ratio (S/D) in maternal non-placental uterine artery, fetal umbilical artery and fetal middle cerebral artery (MCA);Puerpera BP, HR, SpO2, sensory block level, total amount of medication, additional times of controlled amount, labor course, delivery mode, satisfaction score of puerpera analgesia effect, postpartum bleeding amount, puerpera adverse reactions;Fetal heart rate (FHR), Apgar score, umbilical arterial and venous blood gases, gestational age, and birth weight;Neonatal resuscitation, rescue and neonatal complications; | — |
Countries
China