tubercular meningitis and other central nervous system infections
Conditions
Interventions
AIDS/TBM :phytohormone
AIDS/TBM:isoniazid dosage
AIDS/TBM:rifampicin dosage
Sponsors
The Second Affiliated Hospital of Southern University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent before the test, and fully understand the test content, process and possible adverse reactions; 2. Subject 18 years of age and older, both male and female; 3. Diagnosis of HIV infection and tuberculous meningitis in accordance with The Guidelines for DIAGNOSIS and 4. Treatment of AIDS in China (2018 edition) and Guidelines for Diagnosis and Treatment of Tuberculosis (2019 Edition); 5. Hiv-1 antibody was positive by ELISA and confirmed by western blot assay; 6. The pathogen confirmed TB positive; 7. No antiretroviral therapy prior to this treatment; 8. No anti-tuberculosis treatment was received before this treatment.
Exclusion criteria
Exclusion criteria: The investigator determines which subjects are not suitable to participate; Patients with pancreatitis; Pregnancy and lactation patients; Patients complicated with mental system diseases; Patients with severe digestive ulcer; Patients with serious heart, liver and kidney function; Now the drug addicts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| predictor of Tuberculosis Meningitis;the treatment of the phytohormone;incidence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| treatment outcome; | — |
Countries
China
Contacts
Public ContactHui Wang
The Second Affiliated Hospital of Southern University of Science and Technology(The Third People's Hospital of Shenzhen)
Outcome results
None listed