post-stroke aphasia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Clinical participants 1)meet the diagnostic criteria for motor aphasia after stroke 2) Aphasia appears for the first time after stroke 3) Onset time ranged from 15 days to 3 months 4) The severity of aphasia is 0-3 5) Consciousness of consciousness and stable vital signs 6) Aged 45 to 75 years old 7) Volunteer the subjects and agree to sign the informed consent form. fMRI groups 1. Experimental group 1)was selected from the study trial group (before the intervention) 2)dextromanuality 3)The onset involved the language function area 4)Be able to complete the functional nuclear magnetic scanning 5)Volunteer the subjects, and agree to sign the informed consent form 2. Control group 1)was selected from the study trial group (before the intervention) 2)dextromanuality 3)The onset involved the language function area 4) Be able to complete the functional nuclear magnetic scanning 5) Volunteer the subjects, and agree to sign the informed consent form 3. Healthy group 1)Agegender and education level were matched with the patients in the experimental group 2)dextromanuality 3)Be able to complete the functional nuclear magnetic scanning 4)No cognitive impairment no diseases like brain trauma drugand alcohol dependence that may affect brain function and structure; 5)No mental symptoms such as depression; 6)Volunteer the subjects, and agree to sign the informed consent form;
Exclusion criteria
Exclusion criteria: Clinical participants 1)Patients with aphasia caused by other causes 2)Patients with aphasia before this onset 3)combined with severe primary diseases such as liver kidney hematopoietic system and endocrine system There are abnormalities in audio-visual severe cognitive impairment and mental illness which cannot be combined with examination and treatment 4)Patients currently undergoing verbal rehabilitation therapy or rTMS therapy for aphasia 5)Pregnant and lactating women.? fMRI groups: 1)consciousness impairment severe vision hearing impairment and other health assessments can not be completed 2)with cardiac pacemaker nerve stimulator artificial metal heart valve etc. aortic clamp (except for non-paramagnetic properties such as titanium alloy) Those with intraocular metal foreign objects inner ear implants metal prosthesis, metal joints, and ferromagnetic foreign bodies in the body who cannot be scanned or affect the image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Aphasia Battery;Chinese functional communication profile;China?Rehabilitation Research Center Aphasia?Examination;Aphasia Battery of?Chinese; | — |
Secondary
| Measure | Time frame |
|---|---|
| Boston Diagnostic Aphasia Examination;Montreal?Cognitive Assessment;Mini-Mental State Examination;National Institute of Health stroke scale;Modified Rankin Scale,MRS;SAQOL-39 Quality of Life Scale;Stroke-specific Quality of Life Scale;the Health Scale of Traditional Chinese Medicine;Self-Rating?Anxiety?Scale;stroke aphasic depression questionnaire-hospital version; | — |
Countries
China
Contacts
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine