Epidural labor analgesia
Conditions
Interventions
Group F:0.075% ropivacaine +4µg/ mL fentanyl
Group D:0.075% ropivacaine +0.4µg/ mL dexmedetomidine
Group E:0.075% ropivacaine +1.0mg/ mL esticketamine
Sponsors
Zhejiang Xiaoshan Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Pregnant women aged 18 to 40; (2) ASA level 1-2; (3) Height >= 150 cm, weight = 37 weeks; (5) Head position; (6) Cervical dilatation 3-7cm; (7) Vas >= 30mm (0 = no pain, 100 = the most pain).
Exclusion criteria
Exclusion criteria: (1) Contraindications of intraspinal anesthesia; (2) Allergic to narcotic drugs, fentanyl, dexmedetomidine, or esticketamine; (3) Bradycardia; (4) Multiple pregnancy; (5) Preeclampsia; (6) Fetal abnormalities; (7) Refusing to sign the informed consent form; (8) Other conditions: history of cesarean section, long-term use of sedatives or analgesics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effective rate of labor analgesia after 30 minutes of epidural loading.;Total consumption of ropivacaine;PCEA total pressing times and effective pressing times.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basic Maternity Information;NRS (before analgesia, 30min, 60min, uterine opening, fetal delivery);Time of labor;Basic vital signs of parturient women;Mode of delivery;Neonatal outcome; | — |
Countries
China
Contacts
Public ContactZhong Mei
Zhejiang Xiaoshan Hospital
Outcome results
None listed