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Aspirin prevents postoperative peritoneal adhesion by suppressing the TGF-ß1/Smad signaling pathway

Aspirin prevents postoperative peritoneal adhesion by suppressing the TGF-ß1/Smad signaling pathway

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062301
Enrollment
Unknown
Registered
2022-08-01
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peritoneal adhesion

Interventions

Treatment group:Oral aspirin combined with colostomy
Control group:Colostomy

Sponsors

The First Affiliated Hospital of Yangtze University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1). Patients after colostomy; 2). patients with willingness to accept colostomy within 1 year; 3). Patients who have not undergone any abdominal surgery before surgery; 4). No serious systemic diseases, surgical contraindications.

Exclusion criteria

Exclusion criteria: 1). Exclude patients who do not receive colostomy; 2). Excluding severe medical and surgical diseases comorbidities, severe cardiopulmonary dysfunction; 3). Excluding those who are contraindicated in drug use.

Design outcomes

Primary

MeasureTime frame
Adhesion degree;

Countries

China

Contacts

Public ContactYimin Sun
545589834@qq.com+86 18163131529

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026