Fat accumulation
Conditions
Interventions
remimazolam combined with dexmedetomidine and remifentanil group :Remimazolam, dexmedetomidine and remifentanil
Dexmedetomidine and remifentanil group:Dexmedetomidine and remifentanil
Sponsors
Department of Anesthesiology, Plastic Surgery Hospital of Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Perform large-area liposuction involving intraoperative position changes; 2) Complete medical history, physical signs, auxiliary examination, and other clinical medical records; 3) Age 18-60, regardless of gender; 4) BMI >18; 5) Understand and voluntarily participate in the study and sign the informed consent; 6) Have an ASA grade of I.
Exclusion criteria
Exclusion criteria: 1. Allergic history of benzodiazepines and dexmedetomidine; 2. Injection site infection; 3. Mental or nervous system problems, communication disorders and inability to cooperate; 4. History of drug abuse and alcoholism; 5. Pregnant or lactating patients; 6. Intraoperative vital signs are difficult to maintain normal, or severe complications occur and need to be transferred to ICU; 7. Participated in drug clinical trials as a subject within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient satisfaction and surgeon satisfaction scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of patient awakening;The occurrence of adverse reactions;Drug-induced dosage and total dosage;Complementary medication;The duration of induction;Vital signs (heart rate, blood pressure, respiratory rate, BIS value);Sedative effect score;Duration of position change; | — |
Countries
China
Contacts
Public ContactWei Lingxin
Plastic Surgery Hospital of Chinese Academy of Medical Sciences
Outcome results
None listed