Intraoperative use of hemoperfusion in acute Stanford type A aortic dissection with organ malperfusion

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062272

Enrollment

Unknown

Registered

2022-07-31

Start date

2022-08-01

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic dissection

Interventions

Hemoperfusion group:Hemoperfusion

Control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The patient was diagnosed as Stanford type A aortic dissection after strict clinical diagnosis including medical history, typical signs, echocardiography and aortic CTA examination; 2. Onset time =18 years; 4. In CPB, Sun's operation was performed by HCA+SACP; 5. Meet the diagnostic criteria for poor organ perfusion; 6. Sign the informed consent form, and the process of obtaining the informed consent form meets the requirements of relevant regulations.

Exclusion criteria

Exclusion criteria: 1. Pregnant patients; 2. Active bleeding or previous thrombotic thrombocytopenic purpura; 3. Hepatic insufficiency, renal insufficiency or cerebrovascular accident in the past; 4. History of open heart surgery; 5. Long-term use of immunosuppressants or glucocorticoids; 6. Oral anticoagulation or antiplatelet drug therapy within 7 days of onset; 7. The operation time is prolonged due to an accidental operation; 8. Inability to understand and sign the informed consent form.

Design outcomes

Primary

Measure	Time frame
All-cause mortality;Duration of mechanical ventilation;Incidence of acute kidney injury;	—

Countries

China

Contacts

Public ContactWu Xijie

wxjusa@163.com+86 13365910050

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026