PONV
Conditions
Interventions
PDD group:Three antiemetic drugs were injected intravenously before induction
PDgroup:Two antiemetic drugs were injected intravenously before induction
Sponsors
The Second Clinical Medical College,Jinan University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients undergoing gynecological laparoscopic surgery under elective general anesthesia, aged 18 ~ 60 years, ASA physical condition grade I or II.
Exclusion criteria
Exclusion criteria: Patients with pregnancy or lactation, mental or neurological diseases, preoperative application of antiemetics or emetics, previous diagnosis of long QT syndrome, obvious arrhythmia, history of allergy to palonosetron, droperidol and dexamethasone, and history of opioid abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PONV within 6 hours after operation;Incidence of PONV within 6-24 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and degree of nausea within 6 hours after operation;Incidence and degree of vomiting within 6 hours after operation;Intraoperative opioid dosage and sevoflurane dosage;Intraoperative pneumoperitoneum time and operation time;Additional drug dosage after operation;Adverse reactions within 24 hours after operation; | — |
Countries
china
Contacts
Public Contactjiangyuanxu
Outcome results
None listed