menopausal obesity
Conditions
Interventions
Case series:None
Sponsors
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincal Hospital of Chinese Medicine)
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for obesity. 2. Aged 40-60 years. 3. Late menopausal transition and postmenopausal women. 4. The patient entered the menopausal transition or began to develop obesity in the late menopause, and the BMI was normal during the reproductive age. 5. Sign the informed consent form and participate in the study voluntarily. 6. Any TCM syndrome type can be included, but the state of wet syndrome or non-wet syndrome should be judged when included.
Exclusion criteria
Exclusion criteria: 1. Obesity or drug-induced obesity secondary to endocrine diseases; 2. Female muscle obesity patients with body fat percentage < 30%; 3. Patients with unstable angina pectoris, acute myocardial infarction, coronary stent implantation or coronary artery bypass grafting have CVD endpoint outcomes; 4. Severe primary diseases such as liver and kidney insufficiency, hematopoietic system and malignant tumors; 5. Patients with carotid artery stenosis, transient ischemic attack, acute stroke, peripheral vascular disease; 6. Psychiatric patients (schizophrenia, mania, paranoid psychosis and depression with obvious suicidal tendencies); 7. Patients who are participating in other clinical studies; 8. Patients unwilling to cooperate with follow-up visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical examination (Waist circumference, hip circumference, height, weight, blood pressure, body fat ratio);Lipid metabolism;Gycometabolism;Sex hormone binding protein;Carotid plaque size;Metabonomics;Ten-year cardiovascular disease risk assessment;Menopausal symptom score;Cardiovascular end points (coronary heart disease, angina pectoris, stroke, etc.);Hyperlipidemia, diabetes, hypertension and other diseases happened in the cohort study; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;Renal function;Electrocardiogram; | — |
Countries
China
Contacts
Public ContactNie Guangning
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincal Hospital of Chinese Medicine)
Outcome results
None listed