Sepsis
Conditions
Interventions
Sponsors
Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients aged 18-85 years. 2. Sepsis diagnosis criteria: infection + sequentialorgan failure assessment (SOFA)>=2 points.
Exclusion criteria
Exclusion criteria: 1. Lactation or pregnant patients; 2. History of heart disease (coronary heart disease, cardiomyopathy, valvular heart disease, congenital heart disease, arrhythmia), acute coronary syndrome, severe heart failure, cardiothoracic surgery, chest compressions, defibrillation, electrical cardioversion, autoimmune diseases; 3. Cardiac ultrasound indicated moderate to severe mitral and/or aortic valve disease or abnormal regional myocardial wall movement (indicating regional ischemia or previous myocardial infarction); 4. Poor quality cardiac ultrasound caused by patients' uncooperation or lack of operational skills; 5. No blood tests, echocardiography or electrocardiogram were performed during hospitalization; 6. Liver insufficiency (Child-Pugh grade of liver function 10 or above); 7. Renal insufficiency (serum creatinine >=186 µmol/L or glomerular filtration rate < 60 mL/min, or chronic kidneydisease (CKD) grade 3 or above); 8. The researcher judged that it was not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinine;Urea nitrogen;Bilirubin;Alanine aminotransferase;Aspartate aminotransferase;24-hour urine volume;Leukocyte count;C-reactive protein;Procalcitonin;Ejection fraction;Pulmonary artery systolic pressure;Aortic root diameter;Left atrial diameter left atrial diameter;Left ventricular end diastolic diameter;Left ventricular end systolic diameter;Septal thickness;Left ventricular posterior wall thickness; | — |
Countries
China
Contacts
Public ContactLiu Kexuan
Nanfang Hospital of Southern Medical University
Outcome results
None listed