Comparison of novel Photoplethysmographic pulse wave characteristic parameters and Surgical Pleth Index for monitoring different nociception levels in general anesthesia

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062228

Enrollment

Unknown

Registered

2022-07-30

Start date

2022-07-30

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:After general anesthesia induction was completed, the left ulnar nerve was stimulated by different current intensities (20,40,60,80mA)(50Hz)(30s) successively

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Aged 18-60 years, American Society of Anesthesia (ASA) Class I to II, body mass index 18-30 kg /m^2.

Exclusion criteria

Exclusion criteria: 1. Use sedatives, antidepressants and other drugs affecting EEG monitoring recently or before anesthesia induction; 2. Patients with abnormal nervous system function; 3. Patients with severe abnormal functions of heart, lung, liver and kidney; 4. Patients with cardiovascular diseases such as hypertension or taking drugs that affect the cardiovascular system; 5. Diabetic patients; 6. A history of alcohol and drug abuse.

Design outcomes

Primary

Measure	Time frame
Nociception Pleth Index;Surgical Pleth Index;Photoelectric pulse wave signal;	—

Secondary

Measure	Time frame
Reaction entropy;State entropy;Noninvasive blood pressure;Oxygen saturation;	—

Countries

China

Contacts

Public ContactChen Xinzhong

chenxinz@zju.edu.cn+86 571 87061501

Outcome results