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Lung protection effect of driving pressure-guided lung protective ventilation strategy combined with PCV in elderly patients undergoing thoracoscopic radical resection of lung cancer: a randomized controlled trial

Lung protection effect of driving pressure-guided lung protective ventilation strategy combined with PCV in elderly patients undergoing thoracoscopic radical resection of lung cancer: a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062212
Enrollment
Unknown
Registered
2022-07-29
Start date
2022-07-30
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications

Interventions

group A:Volume-Controlled Ventilation (VCV) + Fixed 5cmH2O PEEP
group B:Pressure-Controlled Ventilation (PCV) + Fixed 5cmH2O PEEP
group C:VCV + ?P-guided Individualized PEEP
group D:PCV + ?P-guided Individualized PEEP

Sponsors

Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 60-80 years, BMI 18-30 kg/m^2, ASA?-?; 2. The preoperative pathological diagnosis was lung cancer.

Exclusion criteria

Exclusion criteria: 1. Have received chemoradiotherapy or immunotherapy; 2. Complicated with severe respiratory and cardiovascular diseases; 3. Patients with a history of chest surgery or other surgeries in the last 6 months.

Design outcomes

Primary

MeasureTime frame
postoperative pulmonary complications;—

Secondary

MeasureTime frame
hemodynamic index;arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide;neutrophil elastase;—

Countries

China

Contacts

Public ContactLiu Yi
931160913@qq.com+86 18603465759

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026