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Physiological effects of surgical masks and N95 masks on patients with chronic obstructive pulmonary disease: A Randomized Crossover Trial

Physiological effects of surgical masks and N95 masks on patients with chronic obstructive pulmonary disease: A Randomized Crossover Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062205
Enrollment
Unknown
Registered
2022-07-29
Start date
2022-07-30
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

N95 mask group:In the first stage, the subjects in this group wearing N95 masks to complete the test. After a 24-hour washout period, the subjects in this group wearing surgical masks in the second st
Surgical mask group:In the first stage, the subjects in this group wearing surgical masks to complete the test. After a 24-hour washout period, the subjects in this group wearing N95 masks in the seco

Sponsors

Department of Respiratory and Critical Care Medicine, General Hospital of Xinjiang Military Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Pulmonary function examination was performed and COPD patients were diagnosed as stable according to GOLD grading criteria. 2. Aged 18-80 years. 3. Sufficient physical activity to permit unassisted walking.

Exclusion criteria

Exclusion criteria: 1. Severe respiratory failure with long-term oxygen therapy requires mechanical ventilation; 2. Severe liver and kidney failure; 3. History of acute cardiovascular and cerebrovascular events within 2 months; 4. Have a malignant tumor; 5. Patients with mental disorders; 6. Pregnant patients.

Design outcomes

Primary

MeasureTime frame
partial pressure of CO2;oxygen partial pressure;blood pH;systolic blood pressure;diastolic blood pressure;oxygen saturation;Borg scale score;heart rate;respiratory frequency;hypoxemia;hypercapnia;subjective discomfort (dizziness, headache, dyspnea, fatigue);

Countries

China

Contacts

Public ContactJiang Peng
jipzym@126.com+86 13765803617

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026