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Laparotomy combined with levonorgestrel-releasing intrauterine system: A new surgical method for refractory adenomyosis treatment

Laparotomy combined with levonorgestrel-releasing intrauterine system: A prospective clinical study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062196
Enrollment
Unknown
Registered
2022-07-29
Start date
2022-07-28
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyosis

Interventions

consecutive :none

Sponsors

Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: ? Patients diagnosed with diffuse or giant adenomyosis using B-scan ultrasound or MRI, where the lesion diameter exceeded 5 cm, depth of the uterine cavity was greater than 10 cm and the depth of the lesion was confirmed to reach the endometrium; ? Patients who had previously received drug therapy or laparoscopic lesion resection, but the results were unsatisfactory; ? Women in the age group of 20–45 years, who had no fertility requirements within the last 2 years.

Exclusion criteria

Exclusion criteria: ? Patients diagnosed with gynecological diseases other than adenomyosis, such as cervical lesions and ovarian tumors, as well as those with vaginal inflammation and other contraindications to intrauterine device (IUD) placement; ? Patients with contraindications to progesterone therapy; ? Patients diagnosed with other gynecological conditions that cannot be treated with surgery.

Design outcomes

Primary

MeasureTime frame
CA 125;CA 19-9;Pictorial Blood Loss Assessment Chart ;Visual Analogue Scale;Uterine size;

Countries

China

Contacts

Public ContactYU LI

Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University

liyu19831221@126.com+8618049920519

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026