Nociceptive stimulation during surgery under general anesthesia
Conditions
Interventions
All included patients:no
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Elective surgery patients aged 18-65; ? ASA classification is grade I-III; ? Elective abdominal surgery (gastrointestinal tract, pancreas, gallbladder, liver, etc.) under general anesthesia; ? Voluntarily join the research and sign the informed consent; ? The estimated operation time is more than 2 hours.
Exclusion criteria
Exclusion criteria: ? History of mental or nervous system diseases such as autism, attention deficit hyperactivity disorder, epilepsy, cerebral infarction, etc.; ? History of craniocerebral surgery; ? History of alcohol, opioid or other psychotropic substance abuse; ? Long-term use of sedative drugs; ? Language communication impairment and intellectual disability; ? Allergy to the anesthetics used; ? Family history of malignant hyperthermia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristic changes of exhaled volatile organic compounds in surgery with different stimulation intensities at different times; | — |
Secondary
| Measure | Time frame |
|---|---|
| Characteristic changes of blood in surgery with different stimulation intensities at different times;Characteristic changes of clinical signs in surgery with different stimulation intensities at different times;Correlation of characteristic changes of exhaled volatile organic compounds and changes in blood and clinical signs in surgery with different stimulation intensities at different times; | — |
Countries
China
Contacts
Public ContactYuyi Zhao
West China Hospital of Sichuan University
Outcome results
None listed