FindTrial
Sign In

IL-1Ra gene polymorphism and maternal susceptibility to fever associated with epidural analgesia: a multicenter, observational cohort study

IL-1Ra gene polymorphism and maternal susceptibility to fever associated with epidural analgesia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062171
Enrollment
Unknown
Registered
2022-07-27
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epidural-related maternal fever, ERMF

Interventions

Grouping depends on whether to perform epidural labor analgesia:Nil
fever group vs. non-fever group:Nil

Sponsors

Union Hospital affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Age =18; 2.Singleton primiparas, gestational age =37 weeks; 3.Uterine orifice =2cm; 4.Natural birth

Exclusion criteria

Exclusion criteria: 1.Intraspinal puncture is contraindicated; 2.Hypertension in preeclampsia and pregnancy; 3.premature rupture of membranes; 4.Basal body temperature =37 ?; 5.currently using antibiotics or non-steroidal anti-inflammatory drugs; 6.existing immune dysfunction;

Design outcomes

Primary

MeasureTime frame
oral temperature;Genotype;Plasma IL-1Ra concentration;—

Secondary

MeasureTime frame
Number of vaginal examinations;Whether to use antibiotics;Whether to use oxytocin;Delivery mode;Length of the first stage of labor;Neonatal Apgar score;Neonatal temperature;—

Countries

China

Contacts

Public ContactZhongmeng Lai

Union Hospital affiliated to Fujian Medical University

angerer1980@163.com13395000771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026