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Physiological effects of N95 mask on patients with mild to moderate chronic obstructive pulmonary disease and healthy adults: A Randomized Controlled Clinical Trial

Physiological effects of N95 mask on patients with mild to moderate chronic obstructive pulmonary disease and healthy adults: A Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062166
Enrollment
Unknown
Registered
2022-07-26
Start date
2022-07-26
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

COPD experimental group:Wearing N95 mask
COPD control group:Without wearing N95 face mask
Health experimental group:Wearing N95 mask
Health control group:Without wearing N95 face mask

Sponsors

Department of Respiratory and Critical Care Medicine, General Hospital of Xinjiang Military Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria of COPD patients group: 1. Age 18-80 2. Enough physical activity to allow walking without help 3. The patient was diagnosed with mild to moderate chronic obstructive pulmonary disease by pulmonary function examination. The inclusion criteria of the healthy control group: healthy adults aged 18-80 without cardiopulmonary disease and movement disorders.

Exclusion criteria

Exclusion criteria: Exclusion criteria for COPD patients: 1. Acute exacerbation of chronic obstructive pulmonary disease 2. Patients with severe and extremely severe COPD 3. Severe respiratory failure with long-term oxygen therapy requires invasive mechanical ventilation 4. Severe liver and kidney failure 5.Have a history of acute cardiovascular and cerebrovascular events within 2 months 6. Suffering from malignant tumor 7. Patients with mental disorders 8. Patients with lower extremity dyskinesia 9. Pregnant women. Exclusion criteria of Health Group: pregnant women.

Design outcomes

Primary

MeasureTime frame
PCO2;

Secondary

MeasureTime frame
PO2;PH;Heat Rate,HR;Systolic Blood Pressure,SBP;Diastolic Blood Pressure,DBP;breathing frequency;SpO2;Borg scale;Rating of Perceived Exertion,RPE;Dizzy and Headache;Dyspnea;Exhaust;Lowest SpO2;Fastest heart rate;

Countries

China

Contacts

Public ContactJiang peng

Department of Respiratory and Critical Care Medicine, General Hospital of Xinjiang Military Region

jipzym@126.com13765803617

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026