Analgesic effect of continuous dexmedetomidine infusion on pediatric post-craniotomy: a prospective, randomized controlled study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200062138

Enrollment

Unknown

Registered

2022-07-25

Start date

2022-07-15

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric post-craniotomy pain

Interventions

experimental group :Infusion of dexmedetomidine

control group :Infusion of normal saline

Eligibility

Sex/Gender

All

Age

3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1.Ages of 3-7 years; 2.Elective craniotomy; 3.ASA physical status of I-III; 4.According with the normal range of WHO Child Growth Standards.

Exclusion criteria

Exclusion criteria: 1.Craniotomy through posterior median incision; 2.Patients are allergic to dexmedetomidine or any drugs used in this study; 3.Patients with preoperative disorder of consciousness, Glasgow Coma Scale score is II. 9.Preoperative blood routine, biochemical examination, coagulation function and other laboratory test values exceeded 1.5 times the normal value; 10.Refuse to participate in this trial, or have been included in other clinical trials.

Design outcomes

Primary

Measure	Time frame
Sufentanil consumption 24 hours after operation;	—

Secondary

Measure	Time frame
sedation;Delirium;postoperative pain score;Clinical management satisfaction;sleep quality;	—

Countries

China

Contacts

Public ContactJin Xu

xiehe2000@163.com+86 13693336261

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026