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Correlation between ferroptosis related indicators and kidney disease in patients with type 2 diabetes mellitus

Mechanism of HMGB1-Nrf2 signaling pathway regulating ferroptosis mediated by diabetic kidney disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062128
Enrollment
Unknown
Registered
2022-07-24
Start date
2022-07-25
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus

Interventions

normal proteinuria group:none
microproteinuria group:none
massive proteinuria group:none

Sponsors

The Second Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-75 years old; 2.The diagnosis of T2DM conforms to the"Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes"(2020 edition)

Exclusion criteria

Exclusion criteria: 1.Type 1 diabetes mellitus,monogenic diabetes syndrome and other special types of diabetes; 2.suffering from acute complications of diabetes or other serious complications; 3.Combined with severe liver,kidney,heart disease; 4.Anemia patients or used iron treatment of anemia in the past 3 months; 5.Combined with tumor,inflammation,infection,etc.and affect serum iron metabolism related indicators.

Design outcomes

Primary

MeasureTime frame
Ferroptosis related indicators;—

Secondary

MeasureTime frame
General biochemical indicators;Iron metabolism parameters;—

Countries

China

Contacts

Public ContactChen Yan
cheny99@jlu.edu.cn+86 13578946663

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026