Canceled by the investigator. Changes and correlation analysis of astrocyte markers in patients with obstructive sleep apnea-hypopnea Syndrome

Changes and correlation analysis of astrocyte markers in patients with OSAHS

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200062082

Enrollment

Unknown

Registered

2022-07-21

Start date

2022-07-22

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea hypopnea syndrome

Interventions

snore group:Polysomnography monitoring(PSG)

OSAHS group:Polysomnography monitoring(PSG)

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. young and middle-aged patients aged 18-85 who complained of insomnia in the outpatient department of Neurology of the Second Affiliated Hospital of Chongqing Medical University. All insomnia patients met the American Classification and diagnostic criteria for mental disorders (DSM-IV), with or without snoring history, and all underwent detailed clinical and neurological examinations; 2. The diagnosis of OSAHS by polysomnography (PSG) is based on the OSAS diagnosis and treatment guidelines (Draft) formulated by the respiratory branch of the Chinese Medical Association in 2003, that is, apnea and hypopnea recurred = 30 times during 7h sleep every night, or sleep apnea-hypopnea index (AHI) = 5 times /h; 3. OSAHS was diagnosed for the first time without relevant treatment; 4. No previous history of oronasopharyngeal surgery. Degree judgment: mild AHI: 5-20 times /h; LSaO2(%)85-94; Moderate: 21-40 times /h, lsao2 (%); 80-84 Severe AHI: >40 times /h< 80%.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Consciousness disorder; 2. Severe cognitive, speech, and hearing impairment;3. With chronic obstructive pulmonary disease and cardiogenic pulmonary disease; Patients with severe lung diseases such as bronchial asthma and interstitial lung disease; 4. previous history of cerebral infarction, cerebral hemorrhage, brain surgery, and autoimmune meningitis; 5. Have a history of alcohol dependence and benzodiazepine dependence; 6. Histories of mental illness, such as depression and anxiety; 7. Unable to understand or complete the tester.

Design outcomes

Primary

Measure	Time frame
Apnea hypopnea index;slow wave sleep;	—

Countries

China

Contacts

Public ContactLi Jinfang

lijinfang@hospital.cqmu.edu.cn+86 1398368257

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026