FindTrial
Sign In

Heart rate variability is associated with postoperative cognitive dysfunction in elderly patients

Heart rate variability is associated with postoperative cognitive dysfunction in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062074
Enrollment
Unknown
Registered
2022-07-21
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative neurocognitive dysfunction

Interventions

postoperative cognitive dysfunction group vs. normal group:None

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age=65; 2. American Society of Anesthesiologists (ASA) grade II–III; 3. Preoperative MMSE score: illiteracy > 17, primary school > 20, junior high school and above > 24; 4. Obtain informed consent of patients and their families;

Exclusion criteria

Exclusion criteria: 1. Combined history of severe neurological or mental illness; 2. Compound or only neuraxial? blocks, peripheral nerve blocks; 3. Patients with planned postoperative intensive care unit (ICU) admission; 4. Long-term use of drugs such as chlorpromazine that affect cognitive evaluation; 5. Refuse to participate or be unable to communicate.

Design outcomes

Primary

MeasureTime frame
heart rate variability(HRV);brain derived neurotrophic factor(BDNF);—

Countries

China

Contacts

Public ContactXiaoxia Duan

Southwest Medical University

782348971@qq.com+86 13568635458

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026