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Clinical study of hemoperfusion combined with hemodialysis in patients with maintenance hemodialysis

Multicenter, randomized, controlled clinical study of hemoperfusion combined with hemodialysis in patients with maintenance hemodialysis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062072
Enrollment
Unknown
Registered
2022-07-21
Start date
2022-07-25
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney failure

Interventions

2:Hemoperfusion combined with hemodialysis

Sponsors

The First Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Signed informed consent; 2. Between the ages of 18 and 70, regardless of gender; 3. Recently don't use immunosuppressants and hormones; 4. The duration of maintenance hemodialysis treatment was =3 months, 2-3 times per week, each time was 4 hours, and the dialysis mode was relatively fixed; 5. An abnormal elevation of parathyroid hormone in maintenance hemodialysis patients (PTH>600 pg/ml); 6. Vascular access is an arteriovenous fistula.

Exclusion criteria

Exclusion criteria: 1. Life expectancy <1 year; 2. Allergic to the irrigation equipment; 3. Hemofiltration patients; 4. Unable to cooperate with doctors to complete the research due to mental illness or other subjective and objective reasons; 5. The patient in pregnancy or lactation; 6. Patients with acute infection, malignant tumor, severe liver disease, cerebrovascular disease, heart failure, and critical illness; 7. Previous history of kidney transplantation; 8. Patients with blood transfusion, hemolysis, other clotting disorders, severe bleeding tendency, and active bleeding within 2 months; 9. Irregular dialysis, poor compliance, and inability to cooperate with researchers; 10. Patients who participated in other clinical trials within 3 months prior to enrollment.

Design outcomes

Primary

MeasureTime frame
parathyroid hormone;ß2-microglobulin(MG);Creatinine;Blood urea nitrogen;

Countries

China

Contacts

Public ContactLi Qing

The First Affiliated Hospital of Kunming University

Qingli312@126.com+86 13708762299

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026