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Changes of cardiac function and its influencing factors in patients with diabetic kidney disease

Changes of cardiac function and its influencing factors in patients with diabetic kidney disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200062070
Enrollment
Unknown
Registered
2022-07-21
Start date
2022-07-19
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic kidney disease

Interventions

Case series:none

Sponsors

Huadong Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: If the patients were over 18 years old, diagnosed with diabetes and had no known heart disease, and were willing to participate, the experimental group was eligible for inclusion. Patients with diabetes and confirmed diagnosis of kidney disease were included in the DKD group, and patients with diabetes and had no known kidney disease were included in the DM control group. Healthy individuals without diabetes mellitus and known kidney disease were included in healthy controls.

Exclusion criteria

Exclusion criteria: Known heart disease is defined as heart failure; Coronary artery disease (CAD), including prior myocardial infarction, stable angina, prior percutaneous coronary intervention, or coronary artery bypass surgery; Atrial fibrillation or flutter, left bundle branch block, congenital heart disease, pacemaker or implantable cardioverter defibrillator were excluded. In the diabetic kidney disease group and the non-diabetic kidney disease group, uremia patients already undergoing dialysis should be excluded.

Design outcomes

Primary

MeasureTime frame
Urinary albumin/creatinine;circumferential strain;Early diastolic peak velocity of the mitral ring;

Secondary

MeasureTime frame
Type B natriuretic peptide precursor(ProBNP);

Countries

China

Contacts

Public ContactXiaoli Zhang

Huadong Hospital affiliated to Fudan University

drzhxl@163.com+86 15901907506

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026