Cerebral tumor anesthesia
Conditions
Interventions
Blank control group (Group A) :Routine anaesthesia
Scalp nerve block group (group B) :After induction, scalp nerve block was performed with 0.5% ropivacaine under stable anesthesia
Dexmedetomidine group (group C):Dexmedetomidine was pumped at 1ug/kg for 10min before induction, continuously pumped at 0.4ug/kg during surgery, 0.8ug/Kg was pumped 40min before the end of surgery for
Dexmedetomidine combined with scalp nerve block group (group D) :Dexmedetomidine was pumped at 1ug/kg for 10min before induction, continuously pumped at 0.4ug/kg during surgery, 0.8ug/Kg was pumped 40
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients to be resected for supratentorial tumor (surgical path included frontal, temporal, apical and occipital paths); 2. ASA grade I-III; 3. Age >65 or <18 years; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Contraindications of scalp nerve block: abnormal coagulation function, infection of the puncture site, local anesthetic allergy, etc.; 2. Chronic pain or neuropathic pain, long-term use of painkillers for treatment; 3. Have a history of neurological or mental illness, and take sedative drugs for a long time; 4. Unable to cooperate with researchers for any reason: hearing impairment, language comprehension impairment, mental illness, etc.; 5. Cardiomyopathies or persistent arrhythmias such as permanent atrial fibrillation, sick sinus syndrome, atrioventricular block, sinus bradycardia, or other persistent supraventricular rhythm abnormalities; 6. Advanced hepatic and renal insufficiency; 7. Pregnant or lactating women; 8. For acute or chronic pain, take painkillers within 24 hours; 9. The patient refused to participate or had already participated in another investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hours of postoperative quality of life recovery (QOR-40) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores for resting and exercise at 2h, 6h, 12h, 24h and 48h after extubation; First postoperative relief analgesia time, postoperative analgesia satisfaction 24 hours;Intraoperative traumatic event time, extubation MAP, HR; | — |
Countries
China
Contacts
Public ContactChen Xiuxia
Outcome results
None listed