Asthma
Conditions
Interventions
all:BUD/FOR (160/4.5ug)1 PUFF 2/DAY
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, regardless of gender and race; 2. Recurrent episodes of symptom(wheezing, or shortness of breath, chest tightness, or coughing), symptoms present= 8 weeks; 3. FEV1 = 70%pred before BDTFVE1/FVC>0.7 after BDT; 4. No obvious abnormality in the blood routine except eosinophils and no obvious abnormality in the chest CT; 5. First clinic visit with newly presenting asthma-likely symptoms in 1 year; 6. Childbearing-age women taking effective contraceptive measures during the trial are considered; Agree to participate in this trial and be willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. No willingness for asthma test or due to other reasons. 2. Symptoms cause by respiratory infection within 4 weeks. 3. ACEI, ARB, and beta-blockers are under treatment. 4. Other chronic respiratory diseases such as COPD and interstitial pneumonia; serious comorbidity(e.g. cardiovascular, metabolic, immune, neurological, urinary, and hematological disease) may delay study conduction. 5. History of alcohol, narcotic drug abuse, mental illness, confrontational personality, bad motivation, paranoia, or another mental disease that may affect inform content evaluation in this study. 6. Current smoker; cessation smoking for less than 6 months; cessation smoking for more than 6 months but smoking more than 10 packs/year. 7. Participating in other drug clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Forced expiratory volumone second(FEV1);Maximum Mid-Expiratory Flow(MMEF);asthma control test(ACT);Asthma Control Questionnaire-5(ACQ-5);Cough visual analogue scale(VAS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| peak expiratory flow(PEF); | — |
Countries
China
Contacts
Public ContactMin Zhang
Outcome results
None listed