Painless gastroenteroscopy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 and above who need a colonoscopy or gastroscopy + colonoscopy; 2. The presence of any of the following risk factors for bowel preparation: age > 70 years, history of colon surgery, chronic constipation (constipation meets Rome IV constipation diagnostic criteria), diabetes, Parkinson's disease, history of stroke or spinal cord injury, previous bowel Inadequate oral preparation, body mass index >25 kg/m^2, use of tricyclic antidepressants or anesthetics, use of opioids or other constipation-causing drugs.
Exclusion criteria
Exclusion criteria: 1. Allergy; 2. ASA=?; 3. Patients with diabetes, gastroparesis, gastrointestinal stenosis, or obstruction; 4. Acute perforation of the esophagus, stomach, and duodenum; 5. Cardiovascular disease Diseases, such as serious heart disease such as severe arrhythmia, active myocardial infarction, severe heart failure, etc.; 6. emergency patients; 7. Refusal to sign the informed consent; 8. poor compliance, unable to cooperate with surgery; 9. Those who have participated in clinical trials of other drugs within the past 4 weeks; 10. patients who are accompanied by other conditions and who are considered unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| increased orthostatic pulse rate;Hemodynamics;Bowel preparation quality;Endoscopy Patient Assessment Form;Gastroenteroscopy Questionnaire;blood sugar;electrolyte;Adverse reactions;bowel function recovery time;time of first bowel movement; | — |
Countries
China