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Study on the efficacy and safety of oral lignoftose combined with carbohydrate for intestinal preparation and comfort of patients before painless colonoscopy

Study on the efficacy and safety of oral lignoftose combined with carbohydrate for intestinal preparation and comfort of patients before painless colonoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062035
Enrollment
Unknown
Registered
2022-07-20
Start date
2022-07-31
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless gastroenteroscopy

Interventions

treatment group:The patient fasted after 20:00 the night before. Then drink 50ml of lactulose, if there is no obvious diarrhea, drink 50ml of lactulose after 30 minutes (diarrhea does not need to drin
control group:The patient fasted after 20:00 the night before. Then, take 1 bag of Compound Polyethylene Glycol Electrolyte Powder, add it to 1000ml of warm water, dilute it evenly, and drink it withi

Sponsors

Chongqing general Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 and above who need a colonoscopy or gastroscopy + colonoscopy; 2. The presence of any of the following risk factors for bowel preparation: age > 70 years, history of colon surgery, chronic constipation (constipation meets Rome IV constipation diagnostic criteria), diabetes, Parkinson's disease, history of stroke or spinal cord injury, previous bowel Inadequate oral preparation, body mass index >25 kg/m^2, use of tricyclic antidepressants or anesthetics, use of opioids or other constipation-causing drugs.

Exclusion criteria

Exclusion criteria: 1. Allergy; 2. ASA=?; 3. Patients with diabetes, gastroparesis, gastrointestinal stenosis, or obstruction; 4. Acute perforation of the esophagus, stomach, and duodenum; 5. Cardiovascular disease Diseases, such as serious heart disease such as severe arrhythmia, active myocardial infarction, severe heart failure, etc.; 6. emergency patients; 7. Refusal to sign the informed consent; 8. poor compliance, unable to cooperate with surgery; 9. Those who have participated in clinical trials of other drugs within the past 4 weeks; 10. patients who are accompanied by other conditions and who are considered unsuitable for inclusion by the investigator.

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting rate;

Secondary

MeasureTime frame
increased orthostatic pulse rate;Hemodynamics;Bowel preparation quality;Endoscopy Patient Assessment Form;Gastroenteroscopy Questionnaire;blood sugar;electrolyte;Adverse reactions;bowel function recovery time;time of first bowel movement;

Countries

China

Contacts

Public ContactHuang Chen
272797571@qq.com+86 15823442770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026