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Optimal timing for initiating bronchoscopy with non-intubated reserved spontaneous respiratory intravenous general anesthesia combined with lidocaine topical anesthesia: protocol for a randomized, Double-blind, parallel controlled study

Optimal timing for initiating bronchoscopy with non-intubated reserved spontaneous respiratory intravenous general anesthesia combined with lidocaine topical anesthesia: protocol for a randomized, Double-blind, parallel controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062025
Enrollment
Unknown
Registered
2022-07-19
Start date
2022-07-20
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing elective diagnostic painless bronchoscopy

Interventions

Group A:Waiting 0 minutes
Group B:Waiting 1 minutes
Group C:Waiting 2 minutes
Group D:Waiting 3 minutes

Sponsors

Hanlin Ding
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years; 2. BMI between 18-35 years; 3. Elective painless bronchoscopy; 4. American Society of Anesthesiologists (ASA) class I, II, or III; 5. No severe stenosis or acute infection of the trachea; 6. Patients agree to participate in the study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients requiring emergency bronchoscopy; 2. Hypersensitivity to any of the study drugs; 3. Women during pregnancy; 4. Oxygen saturation less than 90% without oxygen at rest; 5. Basal systolic blood pressure greater than 180 mmHg or less than 90 mmHg; 6. Basal heart rate greater than 110 beats/min or less than 50 beats/min or other severe arrhythmias; 7. Patients with an artificial airway, such as patients with tracheotomy; 8. Psychiatric illness or epilepsy, confusion, abnormal intelligence or cognitive level; 9. Long-term use of narcotic or other analgesic medications; 10. Asthma or an exertional volume of breath per second (FEV1) less than 1L; 11. History of significant cardiovascular disease in the past three months, defined as myocardial infarction, coronary angioplasty or bypass surgery, valve disease or repair, unstable angina; 11. History of major cardiovascular disease in the past 3 months, defined as myocardial infarction, coronary angioplasty or bypass surgery, valve disease or repair, unstable angina, transient ischemic attack, or cerebrovascular accident.

Design outcomes

Primary

MeasureTime frame
Presence of laryngospasm during bronchoscopy;

Secondary

MeasureTime frame
Patient choking score;ent comfort;Patients' satisfaction;Patient Adverse Reactions;

Countries

China

Contacts

Public ContactHanlin Ding
2574076374@qq.com+86 13972060481

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026