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A clinical controlled study of MDT-based radical cystectomy and bladder-preserving comprehensive therapy in the treatment of bladder cancer

A clinical controlled study of MDT-based radical cystectomy and bladder-preserving comprehensive therapy in the treatment of bladder cancer

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062021
Enrollment
Unknown
Registered
2022-07-19
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Cancer

Interventions

Experimental group:The patients in the experimental group received neoadjuvant chemotherapy/immune/radiotherapy before surgery and then underwent maximum transurethral resection of bladder tumor (cTUR
Control group:The control group received neoadjuvant chemotherapy followed by radical resection of bladder cancer.

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with bladder cancer who underwent surgical treatment at Tianjin Medical University General Hospital; 2. The patients underwent preoperative CT/MRI examination and cystoscopy and obtained histopathology to confirm bladder cancer with indications for radical cystectomy and can tolerate surgical treatment;3. Patients were included in the experimental group for those who refused radical cystectomy or who could not tolerate radical cystectomy, and those who underwent radical cystectomy were included in the control group.

Exclusion criteria

Exclusion criteria: 1. Patients who do not meet the indications for radical surgery of bladder cancer; 2. Patients with bladder cancer are generally in poor condition and cannot tolerate surgery or chemotherapy, immunotherapy, and radiotherapy after evaluation;3. Bladder cancer patients who refuse surgery or chemotherapy, immunotherapy, and radiotherapy.

Design outcomes

Primary

MeasureTime frame
Patient assessment of quality of life;After the treatment, color Doppler ultrasonography in the experimental group was reviewed every three months, and cystoscopy was performed if necessary. Chest CT, color Doppler ultrasound and the above examinations are performed every six months.;Timely follow-up to assess quality of life, overall survival rate, disease prognosis and progression by using questionnaires or WeChat groups of patients, and salvage treatment if necessary.;

Countries

China

Contacts

Public ContactXiaoqiang Liu
xiaoqiangliu1@163.com+86 13820915038

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026