Erectile dysfunction and obstructive sleep apnea-hypopnea syndrome in men
Conditions
Interventions
A:The OSAHS standard treatment plan combined with the ED treatment plan was adopted
the OSAHS treatment mainly uses a ventilator for nasal continuous positive airway pressure (CPAP) treatment, the pressure setting starts from 4cm H2O, and the patient adapts to gradually increase the
B:Only treat patients with OSAHS standard treatment, namely CPAP treatment, and require patients to at least ensure that more than 70% of the nights receive CPAP treatment and use it for more than 4 h
C:Only the patients were given standard ED treatment, that is, LIPUS treatment 3 times a week for 2 consecutive weeks
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
Male
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 20-60 years old, male; 2. General health, with stable heterosexual partners for more than 3 months; 3. Diagnosed with obstructive sleep apnea-hypopnea syndrome (OSAHS) by the Department of Respiratory Medicine; 4. Able to tolerate nasal continuous positive airway pressure (CPAP) treatment; 5. Diagnosed as ED by nocturnal penile erection hardness (NPTR) test; 6. No PDE5-i or other ED treatment was used within 2 weeks before the grouping, and there was no obvious drug contraindication; 7. The patients voluntarily agreed to participate in this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. ED caused by serious neurological or serious mental and psychological factors; 2. Those who have previously undergone radical prostatectomy, pelvic surgery or radical prostatectomy and other surgeries affecting erectile function; 3. Any unstable medical, spinal cord injury, abnormal penis anatomy; 4. Those with obstruction of the penile artery or cavernous artery; 5. Those who are recovering from cancer in the past year; 6. Clinically significant chronic blood system diseases, or severe respiratory, digestive, and central nervous system diseases; 7. Those who have confirmed penile hemangioma or cavernous fibrosis; 8. Patients with hypertension with poor blood pressure control (systolic blood pressure = 160 mmHg and/or diastolic blood pressure = 100 mmHg after treatment); 9. Use of anti-androgens and androgen drugs; 10. Postoperative radiotherapy in the pelvic region; 11. Patients with coagulation disorders and using anticoagulants; 12. Have participated in any other medical device or drug clinical research within the past 3 months; 13. Patients who cannot tolerate and/or are unwilling to receive CPAP therapy; 14. Those with a history of chronic mental illness, heavy alcoholism, drug abuse, taking antipsychotic drugs (including sleeping pills and stimulants), and circadian rhythm disorders; 15. Obstructive pulmonary disease and upper airway tumor or disease that compresses the airway; 16. Patients deemed unsuitable for participation in this trial by other investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Polysomnography (PSG) test results;Penile angiography and penile electrophysiology; | — |
Countries
China
Contacts
Public ContactXiaoqiang Liu
Outcome results
None listed