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Using transcranial magnetic stimulation over the cerebellum to investigate the mechanism of cerebellar action in the control of responsive balance in the elderly

Using transcranial magnetic stimulation over the cerebellum to investigate the mechanism of cerebellar action in the control of responsive balance in the elderly

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200062006
Enrollment
Unknown
Registered
2022-07-19
Start date
2022-07-20
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy older adults

Interventions

Experiment group:Real iTBS

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age = 65 years; 2. Absence of skeletal muscle disease, neurological disease, or other underlying conditions affecting balance such as fractures, cerebrovascular disease, vision, and balance problems caused by diabetes mellitus that can affect balance control; 3. No contraindications to iTBS such as epilepsy, brain tumors, intracranial metal or magnetic objects, pacemakers or other implants, and being on psychotropic medications; 4. Suspected or known pregnancy.

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment and insufficient cognitive ability to decide autonomously whether to participate in the experiment; 2. Having severe motor vertigo; 3. Having a headache disorder.

Design outcomes

Primary

MeasureTime frame
Delta-HbO2 change;

Secondary

MeasureTime frame
Timing of muscle activation before and after transcranial magnetic stimulation of the cerebellum;Average EMG signal within 100ms and 100ms-200ms after activation;

Countries

China

Contacts

Public ContactChenfan Gui

West China Hospital, Sichuan University

guichenfan183@126.com+86 13648067172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026