Autoimmune metaplastic atrophic gastritis
Conditions
Interventions
Gold Standard:Pathology is the gold standard for the diagnosis of autoimmune metaplastic atrophic gastritis and H.pylori-induced atrophic gastritis. Meanwhile, serum gastrin, anti-parietal cell antibo
Index test:Serum 
pepsinogen 
 
Serum 
I/II 
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age=18 years old; 2. case group: patients who were diagnosed with autoimmune metaplastic atrophic gastritis had or did not have related gastric lesions, such as gastric neuroendocrine tumors, gastric hyperplastic polyps, gastric adenomas, or adenocarcinoma; 3. control group: patients who were diagnosed with H. pylori-induced atrophic gastritis, serological antibody or urease breath test or histological confirmation of H.pylori infection or eradication treatment.
Exclusion criteria
Exclusion criteria: 1. Age=75 years old; 2. Women who are pregnant or breastfeeding; 3. Malignant tumors of other organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| histology of gastric mucosa;serum gastrin-17;serum pepsinogen I;serum pepsinogen I/II ratio;H.pylori antibody; | — |
Secondary
| Measure | Time frame |
|---|---|
| anti-parietal cell antibody;hemoglobin;serum vitamin B12;serum iron;thyroid function test;thyroid antibodies;intrinsic factor antibody; | — |
Countries
China
Contacts
Public ContactHu Haiyi
Outcome results
None listed