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Effect of restrictive fluid therapy on clinical outcome in patients with high-risk of extubated intro-abdominal infection

Effect of restrictive fluid therapy on clinical outcome in patients with high-risk of extubated intro-abdominal infection

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200061957
Enrollment
Unknown
Registered
2022-07-13
Start date
2022-08-01
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intra-abdominal infection

Interventions

Group 1 :Restrictive fluid therapy
Group 2:Non-restrictive fluid therapy

Sponsors

Lianyungang First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Older than 18 years old; 2. IAI is under control. ; 3. Pass SBT; 4. Patients with tracheal intubation removed for the first time; 5. LUS before extubation (that is, LUS at the end of SBT) > 14 points; 6. Hemodynamic stability for at least 24 hours.

Exclusion criteria

Exclusion criteria: 1. There are contraindications to furosemide; 2. Renal failure.

Design outcomes

Primary

MeasureTime frame
Extubation success rate, 28-day survival rate;

Secondary

MeasureTime frame
ICU length of stay;28 Days survival;

Countries

China

Contacts

Public ContactGu Caihong

Lianyungang First People's Hospital

guch80@163.com+86 18961325020

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026