Hepatic carcinoma
Conditions
Interventions
Group 1 :
Sponsors
First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patient's sex is not limited, and the age is 18 to 75 years old; 2. HCC patients who meet the clinical diagnostic criteria of Diagnostic Criteria for Primary Liver Cancer (2019 Edition) or are diagnosed by histopathological or cytological examination; 3. The liver function is Child Pugh A/B; 4. Accompanied by PVTT of type I-II according to Cheng's classification; 5. Tumor volume accounts for <= 40% of the total liver volume; 6. ECOG score 0-1; 7. Alanine aminotransferase and aspartate aminotransferase < 5 times the upper limit of normal value, urea nitrogen and creatinine < 1.5 times the upper limit of normal value, INR < 1.7 or prothrombin time < 4 s; 8. There is a suitable efferent pathway of portal vein.
Exclusion criteria
Exclusion criteria: 1. Diffuse primary liver cancer; 2. The patient has serious comorbidities, such as hypertension, coronary heart disease and mental illness history; 3. Abnormal coagulation function; 4. Renal dysfunction; 5. Severe iodine contrast agent allergy; 6. Pregnant or breastfeeding women, patients with childbearing potential who are unwilling or unable to take effective contraceptive measures; 7. Have a history of mental illness or psychotropic substance abuse; 8. Patients with combined HIV infection; 9. Those who have participated in clinical trials of other experimental drugs or devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Objective response rate;Disease control rate; | — |
Countries
China
Contacts
Public ContactDechao Jiao
First Affiliated Hospital of Zhengzhou University
Outcome results
None listed