postoperative pain and inflammatory response in patients undergoing modified radical mastectomy for breast cancer
Conditions
Interventions
Experimental group:Continuous erector spinae plane block combined with general anaesthesia
Control group:Sham block combined with general anaesthesia
Sponsors
Huzhou Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old, ASA I-II level; 2. Heart, liver, kidney and endocrine diseases; 3. Normal or slightly decreased lung function; 4. Patients who have not received radiotherapy, chemotherapy and adjuvant immunotherapy before operation; 5. Radical mastectomy combined with axillary lymph node dissection was used in all operations.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to erector spinae plane block; 2. Patients with secondary breast surgery; 3. Patients with severe organ failure; 4. Patients participating in other clinical intervention trials; 5. Patients with a history of mental illness; 6. Patients with morbid obesity (BMI > 40 kg/m2); 7. Patients with a history of narcotic drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesic drug demand;Postoperative adverse reactions;Incidence of post-mastectomy pain syndrome;Inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactYu Liang
Huzhou Central Hospital
Outcome results
None listed