Hepatocellular carcinoma
Conditions
Interventions
Gold Standard:1. Three senior reviewers reached a consensus on the reading results
2. Histopathological examination within 30 days or imaging follow-up for at least 2 years.
Index test:Artificial 
intelligence 
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Patients with high risk factors for HCC, including chronic hepatitis B, liver cirrhosis, and previous or current HCC; 3. Multi-parameter enhanced MRI examination at baseline; 4. Accurate and reliable gold standard results of liver lesions, including histopathological examination within 30 days after baseline MRI examination or imaging follow-up for at least 2 years.
Exclusion criteria
Exclusion criteria: 1. Liver cirrhosis caused by various vascular or congenital causes (such as Budd-Chiari syndrome, hereditary hemorrhagic telangiectasia, etc.); 2. Previously received treatment for focal liver lesions; 3. The quality of multi-parameter enhanced MRI images is poor (such as: severe motion artifacts, lack of scan sequences that make it impossible to evaluate lesions); 4. Histopathological examination or post-baseline imaging follow-up is not enough to confirm the diagnosis of focal liver lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of the AI model;Individual LI-RADS feature classification accuracy of the AI model;LI-RADS categorization accuracy of the AI model;HCC diagnostic accuracy of the AI model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time evaluating per-patient/per-lesion;MR sequence identification accuracy of the AI model; | — |
Countries
China
Contacts
Public ContactBin Song
Department of Radiology, West China Hospital, Sichuan University
Outcome results
None listed