Liver diseases
Conditions
Interventions
Group 2:
Group 1 :
Sponsors
Sichuan Academy of Medical Sciences – Sichuan Provincial People's Hospital (SAMSPH)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective hepatectomy; 2. Age 18-80 years old; 3. ASA classification I to III.
Exclusion criteria
Exclusion criteria: 1. Long-term use of opioids; 2. Weight less than 40 kg or greater than 100 kg; 3. Distant metastasis of cancer to other organs; 4. Severe hepatic impairment (aspartate aminotransferase greater than 2.5 times the upper limit of normal value) or severe renal impairment (creatinine clearance rate less than 60ml/min) and heart failure defined as New York Heart Association Class IV; 5. Inability to properly describe postoperative pain to investigators (eg, speech impairment, neuropsychiatric impairment); 6. Patients admitted to ICU after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of moderate to severe pain within 24 hours (VAS >= 4); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of moderate to severe pain within 48 hours;Incidence of moderate to severe pain within 72 hours;Cumulative morphine dosage; | — |
Countries
China
Contacts
Public ContactZeng Si
University of Electronic Science and Technology of China
Outcome results
None listed