Breast cancer
Conditions
Interventions
Experimental group:Endoscopic breast conserving surgery
Control group:Traditional breast conserving surgery
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Preoperative pathological examination confirmed stage I or II invasive breast cancer or ductal carcinoma in situ; 2. The tumor size belongs to T1 and T2 stages (if the patient has received neoadjuvant therapy, the stage after neoadjuvant therapy shall prevail), the ratio of tumor volume to breast gland volume is appropriate, and ideal breast shape can be obtained after surgery; 3. Clinical and imaging examinations are clearly a single lesion confined to the gland, without invading the skin, subcutaneous tissue, pectoralis major and nipple-areolar complex; 4. The patient has a clear willingness to breastfeed, and postoperative radiotherapy can be standardized.
Exclusion criteria
Exclusion criteria: 1. The maximum diameter of the tumor before or after neoadjuvant therapy is >= 5 cm; 2. Breast cancer in the central region and the distance from the nipple <= 2 cm; 3. Tumor resection margins are continuously positive, and re-excision cannot guarantee negative resection margins; 4. Inflammatory breast cancer; 5. There used to be scars on the surface of the breast skin; 6. The patient is a carrier of BRCA1 and BRCA2 gene mutations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cosmetic effect;Breast satisfaction;Psychosocial well-being;Sexual well-being;Chest well-being;Short-term safety;Long-term safety;Economic cost of health; | — |
Countries
China
Contacts
Public ContactZhenggui Du
West China Hospital, Sichuan University
Outcome results
None listed