Stomach tumor, colon, rectal tumor
Conditions
Interventions
Test group:Granisetron
Sponsors
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1. Elderly patients with ASA class I or II; 2. Aged 60-74 years (the population at this stage is defined as young old people by WHO); 3. 18.5 <= BMI <= 23.9; 4. The patient was diagnosed with gastric or intestinal tumor at Run Run Shaw Hospital and underwent laparoscopic gastric or intestinal resection as scheduled; 5. Patients with one or more high-risk factors for postoperative nausea and vomiting (PONV); 6. Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe history of cardiovascular and cerebrovascular diseases; 2. Patients with a history of severe arrhythmia, cardiac insufficiency, or severe heart valve disease; 3. history of serious respiratory diseases; 4. Hypertensive patients taking ACEI or ARB for a long time or patients with secondary hypertension or above; 5. Hyperthyroidism; 6. Liver and kidney insufficiency; 7. Untreated hyperglycemia or those with poor treatment effect; 8. Patients who are allergic to anesthetics (such as propofol and cisatracurium besylate); 9. Gastrointestinal obstruction, allergic to granisetron or related compounds; 10. Vulnerable groups, including mentally ill, critically ill patients, cognitively impaired, pregnant women, illiterate, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean arterial pressure;Blood pressure;heart rate;Entropy index;oxygen saturation;end-tidal carbon dioxide; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine output;Infusion volume; | — |
Countries
China
Contacts
Public ContactGang Chen
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Outcome results
None listed