painless delivery
Conditions
Interventions
Group of low-dose esketamine:Ropacaine 100 mg+Esketamine 50 mg
Group of high-dose esketamine:Ropacaine 100 mg+Esketamine 100 mg
Group of Sufentanil:Ropacaine 100 mg+Sufentanil 50 ug
Sponsors
Qilu Hospital of Shandong University Dezhou Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. ASA I level, willing to give birth without pain; 2. The mother is a singleton, head position, no head-pelvic disproportion; 3. Height > 1.5 m, gestational period 38-42 weeks; 4. No coagulation dysfunction, no history of mental illness.
Exclusion criteria
Exclusion criteria: 1. Those with known allergy to ketamine; 2. Patients with intellectual disabilities; 3. Those who have a history of surgery or are receiving other analgesics and hormone therapy; 4. Those who are taking drugs that have the same pharmacological effect or interact with ketamine; 5. Those with nervous system or neuromuscular dysfunction; 6. Those with mental illness; 7. Before this study, there is a history of exposure to psychotropic drugs, alcohol, and tobacco products for more than 2 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesia score;Fetal score;Depression score;nausea; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sports score; | — |
Countries
China
Contacts
Public ContactNiu Li
Qilu Hospital of Shandong University, Dezhou Hospital
Outcome results
None listed