Postoperative cognitive impairment
Conditions
Interventions
control group:None
Propofol group (group P):Using Propofol for anesthesia induction and maintenance
Fospropofol Disodium group (group F):Using Fospropofol Disodium for anesthesia induction and maintenance
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine,University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years; 2. ASA classification I-III, right-handed; 3. No history of radiotherapy and chemotherapy; 4. Elective hip arthroplasty. The control group only needs to meet the first three inclusion criteria, and the experimental group needs to meet all the inclusion criteria.
Exclusion criteria
Exclusion criteria: 1. Patients with schizophrenia, epilepsy, Parkinson's disease and myasthenia gravis; 2. Communication difficulties due to coma, severe dementia, language disorder, or inability to cooperate due to other diseases; 3. Have craniocerebral trauma or other craniocerebral diseases; 4. Abusers of anesthetic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function questionnaire score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic index; | — |
Countries
China
Contacts
Public ContactKeqiang He
Department of Anesthesiology, the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China
Outcome results
None listed