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Effect of High-Frequency rTMS Combined with Motor Training on Plastic Reorganization of Brain Functional Networks in Stroke Based on fNIRS

Research and development of dynamic quantitative evaluation and intelligent rehabilitation training system for limb movement dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200061885
Enrollment
Unknown
Registered
2022-07-06
Start date
2022-07-05
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

stroke group:Bilateral upper limb motor training
stroke group:High-frequency rTMS combined with bilateral upper limb motor training
control group:Bilateral upper limb motor training
control group:High frequency rTMS combined with bilateral upper limb motor training

Sponsors

National Research Center for Rehabilitation Technical Aids
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: For stroke: 1. First stroke, confirmed by head CT or MRI; 2. Mild, moderate or severe motor dysfunction; 3. No obvious cognitive and speech dysfunction and ability to understand and follow instruction. For healthy control: 1. No hypertension or good blood pressure control; 2. No cardiac conduction system diseases; 3. No history of epilepsy or family history of epilepsy.

Exclusion criteria

Exclusion criteria: Stroke patients: 1. Previous history of stroke, traumatic brain injury, or brain tumor; 2. Complicated with serious heart, lung, liver, kidney dysfunction or other serious physical diseases; 3. Previous epilepsy and family history of epilepsy; 4. Metal implanted in the human body, such as cardiac pacemaker, skull metal, etc.; 5. New infarction foci or secondary bleeding and deterioration of the condition; 6. Patients with severe cervical spondylosis, including severe cervical conical stenosis and cervical instability. Healthy control: 1. Metal implants in the head and neck.

Design outcomes

Primary

MeasureTime frame
cerebral oxygenation;Clinical function preformance;

Countries

China

Contacts

Public ContactLi Zengyong

Beihang University

lizengyong@nrcrta.cn+86 10 58122886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026