recurrent nasopharyngeal carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of malignant tumor of nasopharynx or skull base; 2. Metastatic retropharyngeal lymph nodes for image findings; 3. Stage rT1,rT2,rT3 or rT4 and surgically resectable; 4. Aged >= 18 years; 5. Sign of inform consent on metastatic retropharyngeal lymph nodes resection; 6. No risk of recent bleeding; 7. Without distant metastasis; 8. Sufficient organ function; 9. General physical condition can tolerate general anesthesia.
Exclusion criteria
Exclusion criteria: 1. With distant metastasis; 2. With uncontrolled intercurrent illnesses which will interfere with the ability to undergo therapy; 3. With prior malignancy (excluding adequately treated basal cell or squamous cell skin cancer, in-situ cervical cancer); 4. Any contradiction to surgery; 5. With serious autoimmune disease; 6. Have any co-existing condition that would preclude full compliance or safety with the study; 8. Presence of a significant neurological or psychiatric disease, including dementia and seizures; 7. Presence of a significant neurological or psychiatric disease, including dementia and seizures; 8. Uncontrolled infectious diseases; 9. Female patients who are at pregnancy or lactation; 10. Without personal freedom or independent civil capacity; 11.Other situations that are not suitable for grouping.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| R0 resection rate of surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total resection rate of imaging;surgery-related complications;life quality;disease-free survival; | — |
Countries
China
Contacts
Eye & ENT Hospital of Fudan University