Sepsis
Conditions
Interventions
Sponsors
Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ICU/EICU stay for more than 7 days; 2. Aged 18-85 years; 3. Those who meet the diagnostic criteria for sepsis; 4. Those who meet the diagnostic criteria for gastrointestinal dysfunction; 5. Those who meet the gastrointestinal dysfunction score >= 1; 6. Those who meet the APACHE II score >= 15 points; 7. Those who voluntarily or family members agree and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who do not have the conditions for enteral feeding; 2. Those who have gastrointestinal dysfunction caused by primary gastrointestinal diseases or trauma; 3. Those who are diagnosed with gastrointestinal malignant tumors or other advanced malignant tumors; 4. Those who do not have bladder Those with pressure measurement conditions (bladder injury or contracture, urethral stenosis or rupture, etc.); 5. Those who used glycerin enema, mosapride, lactulose and other drugs to improve gastrointestinal function within 1 week before the test; 6. Those suffering from mental disorders; 7. Those who are pregnant or breastfeeding; 8. Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| APACHE II score, acute physiology and chronic health evaluation scoring system;TCM symptom score;serum lymphokine;Gastrointestinal Dysfunction Score;Intestinal fatty aid binding protein;intra-abdominal pressure;Peripheral blood T lymphocyte subsets; | — |
Countries
China
Contacts
Public ContactHuang Ye
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed