Bone Defects
Conditions
Interventions
Test group and control group:Implanted Bone Meal Covered with Biofilm
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years, male or female; 2. Patients voluntarily participate in the trial and sign the informed consent form (ICF); 3. Patients requiring tooth extraction; 4. Patients with good oral hygiene habits; 5. The local wound, if any, can be completely closed by surgical suture.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of osteoporosis and have received bisphosphonate therapy; 2. Patients with a history of chemotherapy and radiotherapy of maxillofacial, nasopharyngeal, neck within the past 5 years; 3. Patients have severe degenerative diseases; 4. Patients with local infection; 5. Patients with severe systemic diseases; 6. Patients with systemic or local bone diseases such as bone cyst, bone tuberculosis, osteitis, bone neoplasm, etc.; 7. Pregnant or lactating women; 8. Patients with pregnancy plans within 6 months; 9. Long-term use of special drugs such as hormones, anticoagulants, etc.; 10. Patients with psychosis, psychological disorders and neurological diseases, such as epilepsy; 11. Patients with endocrine and metabolic diseases, blood system diseases and uncontrolled cardiovascular disorders; 12. Patients who smoke more than ten cigarettes per day or have very poor oral hygiene habits; 13. Patients with severe bone defects; 14. Diabetic patients; 15. Subjects with severe allergic constitution; 16. Other conditions considered unsuitable for participation in the trial by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change value of alveolar ridge height at immediate postoperative time and at 6 months after surgery;wound healing at 1 week, 1 month, 3 months and 6 months after surgery;The change value of alveolar ridge width at immediate postoperative time and at 6 months after surgery; | — |
Countries
China
Contacts
Public ContactWang Xiao
Peking University Third Hospital
Outcome results
None listed